Wide-field extended-resolution fluorescence microscopy with standing surface-plasmon-resonance waves.

نویسندگان

  • Euiheon Chung
  • Yang-Hyo Kim
  • Wai Teng Tang
  • Colin J R Sheppard
  • Peter T C So
چکیده

The resolution of conventional surface-plasmon-resonance (SPR) imaging has been limited by the diffraction nature of light. A wide-field extended-resolution optical imaging technique, standing-wave SPR fluorescence (SW-SPRF) microscopy, has been developed. Based on evanescent SPR standing waves, SW-SPRF provides lateral resolution approaching 100 nm and offers the advantages of significant signal enhancement and background-noise reduction. SW-SPRF has the potential for sensitive biomolecular detection, nanoscale imaging, and lithographic applications.

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عنوان ژورنال:
  • Optics letters

دوره 34 15  شماره 

صفحات  -

تاریخ انتشار 2009